A study of 36, 764 veterans published in PLoS One – a peer-reveiwed online scientific journal – this year showed 31% of that veteran population already had chronic kidney disease prior to to being diagnosed with diabetes.  Results suggest that evidence of CKD is common among veterans before a diabetes diagnosis.  Treatment of these conditions at VA hospitals is common and research into treating these diseases is being undertaken. In 2015, Dr. Adam Whaley-Connell and the TVAMRF partnered with a sponsor to conduct a clinical trial at the Harry S. Truman Memorial VA Hospital on new medication that works to treat both conditions.

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According to the VA Health Administration website – chronic kidney disease is common in the Veteran population. It is estimated to affect one out of six Veterans receiving health care at VA.  Dr. Kunal Chaudhary and the TVAMRF are collaborating with a sponsor to conduct two clinical trials at the Truman VA studying the effects of a new kind of drug therapy for veterans being treated for this disease.  The TVAMRF provides clinical study nursing support, data input and reporting as well as provides compliance work as well.

Nephrology Investigators

Vincent DeMarco, PhD

Vincent DeMarco, PhD

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Nephrology: Impact of Empagliflozin & Linagliptin Combination Therapy on Cardiovascular and Kidney Disease Progress in Rodent Models of Obesity

Cardiovascular: Impact of Dual Acting Angiotensin-Receptor/Neprilysin Inhibitor (ARNi) Therapy on Abnormal Cardiac, Vascular and Renal Function in Male Zuker Rats

Endocrinology: Impact of Sodium Glucose Transporter 2 (SGLT2) Inhibition on Cardiac Function in a Rodent Model of Diabetes

Adam Whaley Connell, DO

Adam Whaley Connell, DO

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Safety and Efficacy of Finerenone & Standard of Care on the Progression of Kidney Disease in Subjects with Type 2 Diabetes Mellitus and the Clinical Diagnosis of Diabetic Kidney Disease

Kunal Chaudhary, MD

Kunal Chaudhary, MD

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Phase 3, Randomized, Open-Label, Active-Controlled Study Evaluating The Efficacy And Safety Of Oral Vadadustat for the Maintenance Treatment of Anemia In Subjects with Non-Dialysis-Dependent Chronic Kidney Disease (Ndd-Ckd) PRO2TECT CONVERSION (“Protocol”)

Clinical Support Team

Tim Morris

Tim Morris

Regulatory and Compliance Coordinator

Charla Jay, RN, BSN, CCRP

Charla Jay, RN, BSN, CCRP

Nurse Study Coordinator

R. Joe Montogmery, RN

R. Joe Montogmery, RN

Nurse Study Coordinator

Danielle Fields, PharmD

Danielle Fields, PharmD

Research Pharmacist

Mike Quinata, MBA

Mike Quinata, MBA

Contracts and Budgets